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Publications and Awards of the Neuropharma Lab from UnB
Papers published
29. SILVA, J.C.; NETO, L.M.; NEVES, R.C.; GONÇALVES, J.C.; TRENTINI, M.M.; MUCURY-FILHO, R.; SMIDT, K.S.; FENSTERSEIFER, I.C.; SILVA, O.N.; LIMA, L.D.; CLISSA, P.B.; VILELA, N.; GUILHELMELLI, F.; SILVA, L.P.; RANGEL, M.; KIPNIS, A.; SILVA-PEREIRA, I.; FRANCO, O.L.; JUNQUEIRA-KIPNIS, A.P.; BOCCA, A.L.; MORTARI, M.R. Evaluation of the antimicrobial activity of the mastoparan Polybia-MPII isolated from venom of the social wasp Pseudopolybia vespiceps testacea (Vespidae, Hymenoptera). International Journal of Antimicrobial Agents, v. 49, p. 1-14, 2017.
28. OLIVEIRA JUNIOR, N.G.; FERNANDES, G.R.; COSTA, F.F.; CARDOSO, M.H.; CANDIDO, E.D.S.; GARRONE NETO, D.; MORTARI, M.R.; SCHWARTZ, E.F.; FRANCO, O.L.; ALENCAR, S.A. Venom gland transcriptome analyses of two freshwater stingrays (Myliobatiformes: Potamotrygonidae) from Brazil. Scientific Reports, v. 6, p. 21935-14, 2016.
27. NEVES, R.C.; TRENTINI, M.M.; SILVA, J.C.; SIMON, K.S.; BOCCA, A.L.; SILVA, L.P.; MORTARI, M.R.; KIPNIS, A. ; JUNQUEIRA-KIPNIS, A.P. Antimycobacterial Activity of a New Peptide Polydim-I Isolated from Neotropical Social Wasp Polybia dimorpha. Plos One, v. 11, p. e0149729-21, 2016.
26. ANJOS, L.C.; GOMES, F.M.M; DO COUTO, L.L.; MOURÃO, C.A.; MOREIRA, K.G.; SILVA, L.P.; MORTARI, M.R.. Anxiolytic activity and evaluation of potentially adverse effects of a bradykinin-related peptide isolated from a social wasp venom. Life Sciences, v. 149, p. 153-159, 2016.
25. AGUSTINHO, D.P.; DE OLIVEIRA, M.A.; TAVARES, A.H.; DERENGOWSKI, L.; STOLZ, V.; GUILHELMELLI, F.; MORTARI, M.R.; KUCHLER, K.; SILVA-PEREIRA, I. Dectin-1 is required for miR155 upregulation in murine macrophages in response to. Virulence, v. 1, p. 00-00, 2016.
24. BUCK, C.H.; RUGGIERO, R.N.; FERNANDES, A.; BUENO-JUNIOR, L.; PEREIRA JUNIOR, A.; MARTI-BARROS, D.; GOUVEIA JR, A.; CRESPO-LOPEZ, M.E.; MORTARI, M.R.; GARCIA-CAIRASCO, N.; QUILLFELDT, J.; HEDIN-PEREIRA, C.; FROES, M.M. Semana Nacional do Cérebro 2014: grandes eventos em foco. Neurociências (Rio de Janeiro), v. 12, p. 4-20, 2016.
23. GONÇALVES, J.C.; RANGEL, M.; MAYER, A.B.; ALVES, E.; MOREIRA, K.G.; SILVA, L.P.; MORTARI, M.R. Antinociceptive properties of the mastoparan peptide Agelaia-MPI isolated from social wasps. Toxicon, v. 120, p. 15-21, 2016.
22. MORTARI, M.R.; CUNHA, A.O.S.; CAROLINO, R.O.G.; SILVA, J.C.; LOPES, N.P.; SANTOS, W.F. Evaluation of Thr-bradykinin purified from wasp venom in the choline uptake of mammal cortices. Pharmaceutical Biology, v. 1, p. 1-3, 2016.
21. GOMES, F.M.M.; PANIAGO, C.K.; FREIRE, D.O.; SOUZA, A.C.B.; LIMA, M.R.; JÚNIOR, N.G.O.; FRANCO, O.L.; MORTARI, M.R. Anxiolytic-like effect of a novel peptide isolated from the venom of the social wasp Synoeca surinama. Toxicon, v. 122, p. 39-42, 2016.
20. GUILHELMELLI, F.; VILELA, N.; SMIDT, K.S.; DE OLIVEIRA, M.A.; DA CUNHA MORALES ÁLVARES, A.; RIGONATTO, M.C.L.; DA SILVA COSTA, P.H.; TAVARES, ALDO H.; FREITAS, S.M.; NICOLA, A.M.; FRANCO, O.L.; DERENGOWSKI, L.S.; SCHWARTZ, E.F.; MORTARI, M.R.; BOCCA, A.L.; ALBUQUERQUE, P.; SILVA-PEREIRA, I. Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms. Frontiers in Microbiology, v. 7, p. 1-14, 2016.
19. SILVA, J.C.; OLIVEIRA, F.N.; MOREIRA, K.G.; MAYER, A.B.; FREIRE, D.O.; CHEROBIM, M.D.; DE OLIVEIRA JUNIOR, N.G.; SCHWARTZ, C.A.; SCHWARTZ, E.F.; MORTARI, M.R. Pathophysiological effects caused by the venom of the social wasp Synoeca surinama. Toxicon, p. 41-48, 2016.
18. SOUZA, A.C.O.; NASCIMENTO, A.L.; DE VASCONCELOS, N.M.; JERÔNIMO, M.S.; SIQUEIRA, I.M.; R-SANTOS, L.; CINTRA, D.O.S.; FUSCALDI, L.L.; PIRES JÚNIOR, O.R.; TITZE-DE-ALMEIDA, R.; BORIN, M.F.; BÁO, S.N.; MARTINS, O.P.; CARDOSO, V.N.; FERNANDES, S.O.; MORTARI, M.R.; TEDESCO, A.C.; AMARAL, A.C.; FELIPE, M.S.S.; BOCCA, A.L. Activity and in vivo tracking of Amphotericin B loaded PLGA nanoparticles. European Journal of Medicinal Chemistry, v. 95, p. 267-276, 2015.
17. SARMIENTO, B.E.; RANGEL, M.; GONÇALVES, J.C.; PEREIRA, L.; REGO, S.; CAMPOS, L.A.; HADDAD, V.; MORTARI, M.R.; SCHWARTZ, E.F. First report of the characterization of the pathophysiological mechanisms caused by the freshwater catfish Pimelodus maculatus (order: Siluriformes). Toxicon, p. 55-62, 2015.
16. PIC-TAYLOR, A.; MOTTA, L.G.; MORAIS, J.A.; JUNIOR, W.M.; SANTOS, A.F.A.; CAMPOS, L.A.; MORTARI, M.R.; ZUBEN, M.V.V.; CALDAS, E.D. Behavioural and neurotoxic effects of ayahuasca infusion (Banisteriopsis caapi and Psychotria viridis) in female Wistar rat. Behavioural Processes, v. 118, p. 102-110, 2015.
15. FACHIM, H.; MORTARI, M.R.; GOBBO, L.; SANTOS, W.F. Neuroprotective activity of parawixin 10, a compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae) in rats undergoing intrahippocampal NMDA microinjection. Pharmacognosy Magazine, v. 11, p. 579, 2015.
14. MONGE-FUENTES, V.; GOMES, F.M.M.; CAMPOS, G.A.A.; SILVA, J.C.E.; BIOLCHI, A.; ANJOS, L.C.; GONCALVES, J.C.; LOPES, K.S.; MORTARI, M.R. Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders. The Journal of Venomous Animals and Toxins Including Tropical Diseases, v. 21, p. 1-9, 2015.
13. CARNEIRO, M.L.B.; LOPES, C.A.P.; MIRANDA-VILELA, A.L.; JOANITTI, G.A.; DA SILVA, I.C.R.; MORTARI, M.R.; DE SOUZA, A.R.; BÁO, S.N. Acute and subchronic toxicity of the antitumor agent rhodium (II) citrate in Balb/c mice after intraperitoneal administration. Toxicology Reports, v. 2, p. 1086-1100, 2015.
12. SILVA, J.C.; MONGE-FUENTES, V.; GOMES, F.M.M.; LOPES, K.S.; ANJOS, L.C.; CAMPOS, G.A.A.; ARENAS, C.J.; BIOLCHI, A.M.; GONÇALVES, J.C.; GALANTE, P.; CAMPOS, L.A.; MORTARI, M.R. Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools. Toxins, v. 7, p. 3179-3209, 2015.
11. GELFUSO, E.A.; ROSA, D.S.; FACHIN, A.L.; MORTARI, M.R.; CUNHA, A.O.S.; BELEBONI, R.O. Anxiety: A Systematic Review of Neurobiology, Traditional Pharmaceuticals and Novel Alternatives from Medicinal Plants. CNS & Neurological Disorders. Drug Targets, v. 13, p. 150-165, 2014.
10. BUCK, C.H.; RUGGIERO, R.N.; FERNANDES, A.; BUENO-JUNIOR, L.; PEREIRA JUNIOR, A.; MARTI-BARROS, D.; GOUVEIA JR, A.; CRESPO-LOPEZ, M.E.; MORTARI, M.R.; GARCIA-CAIRASCO, N.; QUILLFELDT, J.; HEDIN-PEREIRA, C.; FROES, M.M. II Semana Nacional do Cérebro (SNC/2013): popularizando as neurociências. Revista Neurociências, v. 10, p. 73-84, 2014.
9. NÓBREGA, M.M.; VINECKY, F.; MOREIRA, K.G.; MORTARI, M.R.; BLOCH JR, C. Synthesis, purification, characterization, and antinociceptive activity of opioids peptides. BMC Proceedings, v. 8, p. P184, 2014.
8. LIBERATO, J.L. ; GODOY, L.D.; MORTARI, M.R.; GOBBO-NETO, L.; LOPES, N.P.; SANTOS, W.F. Parawixin10: A new natural compound from Parawixia bistriata spider venom that presents neuroprotective, memory-saving, and disease-modifying effects in the pilocarpine model of TLE in Wistar rats. Epilepsy & Behavior, v. 38, p. 196, 2014.
7. GELFUSO, E.A.; LIBERATO, J.L.; CUNHA, A.O.S.; MORTARI, M.R.; LOPES, N.P.; BELEBONI, R.O.; SANTOS, W.F. Parawixin2, a novel non-selective GABA uptake inhibitor from Parawixia bistriata spider venom, inhibits pentylenetetrazole-induced chemical kindling in rats. Neuroscience Letters, v. 543, p. 12-16, 2013.
6. MOURÃO, C.B.F.; OLIVEIRA, F.N.; CARVALHO, A.C.; ARENAS, C.J.; DUQUE, H.M.; GONÇALVES, J.C.; MACÊDO, J.K.A.; GALANTE, P.; SCHWARTZ, C.A.; MORTARI, M.R.; ALMEIDA SANTOS, M.F.M.; SCHWARTZ, E.F. Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom. Toxicon, v. 61, p. 129-138, 2013.
5. OLIVEIRA, F.N.; MORTARI, M.R.; CARNEIRO, F.P.; GUERRERO-VARGAS, J.A.; SANTOS, D.M.; PIMENTA, A.M.C.; SCHWARTZ, E.F. Another record of significant regional variation in toxicity of Tityus serrulatus venom in Brazil: A step towards understanding the possible role of sodium channel modulators. Toxicon, v. 73, p. 33-46, 2013.
4. COUTO, L.L.; ANJOS, L.C.; MOURÃO, C.A.; FERREIRA, L.B.; MORTARI, M.R. Anticonvulsant and anxiolytic activity of the peptide fraction isolated from the venom of the social wasp Polybia paulista. Pharmacognosy Magazine, v. 8, p. 292, 2012.
3. GATI, C.D.C.; MORTARI, M.R.; SCHWARTZ, E.F. Towards therapeutic applications of arthropod venom K+-channel blockers in CNS neurologic diseases involving memory acquisition and storage. Journal of Toxicology, v. 2012, p. 1-21, 2012.
2. SCHWARTZ, E.F.; MOURÃO, C.B.F.; CAMARGOS, T.S.; Moreira, K.G.; MORTARI, M.R. Arthropod venoms: a vast arsenal of insecticidal neuropeptides. Biopolymers, v. 98, p. 385-405, 2012.
1. MORTARI, M.R.; COUTO, L.L.; DOS ANJOS, L.C.; MOURÃO, C.B.F.; CAMARGOS, T.S.; VARGAS, J.A.G.; OLIVEIRA, F.N.; GATI, C.D.C.; SCHWARTZ, C.A.; SCHWARTZ, E.F. Pharmacological characterization of Synoeca cyanea venom: An aggressive social wasp widely distributed in the Neotropical region. Toxicon, v. 59, p. 163-170, 2012.
Book chapters published
1. MORTARI, M.R.; CUNHA, A.O.S. New perspectives in drug discovery using neuroactive molecules from the venom of arthropods. In: Gandhi Rádis Baptista. (Org.). An Integrated View of the Molecular Recognition and Toxinology - From Analytical Procedures to Biomedical Applications. 1ed.: Intech open acess publisher, 2013, v. 1, p. 1-26.
Patents
6. BLOCH JR, C.; VINECKY, F.; MOREIRA, K.G.; MORTARI, M.R. Opioid Peptide. 2015, Brazil. Patent: Privilege of Innovation. Registration number: WO2016026017A1, Registration institution: WIPO - World Intellectual Property Organization.
5. BLOCH JR, C.; NÓBREGA, M.M.; MOREIRA, K.G.; MORTARI, M.R. Opioid Peptide. 2015, Brazil. Patent: Privilege of Innovation. Registration number: WO2016026016A1, Registration institution: WIPO - World Intellectual Property Organization.
4. BLOCH JR, C.; VINECKY, F.; MOREIRA, K.G.; MORTARI, M.R. Peptídeos opióides. 2014, Brazil. Patent: Privilege of Innovation. Registration number: BR1020140203486, Registration institution: INPI - National Institute of the Industrial Property. Deposit: 08/18/2014.
3. BLOCH JR, C.; NÓBREGA, M.M.; MOREIRA, K.G.; MORTARI, M.R. Peptídeos opióides. 2014, Brazil. Patente: Privilege of Innovation. Registration number: BR1020140203524, Registration institution: INPI - National Institute of the Industrial Property. Deposit: 08/18/2014.
2. MORTARI, M.R.; GONÇALVES, J.C.; SCHWARTZ, E.F.; RIBEIRO, P.G.; SILVA, L.P. Peptide modified from the venom of the social wasp and its use as analgesics. 2014, Brazil. Patent: Privilege of Innovation. Registration number: BR1020140205101, Registration institution: INPI - National Institute of the Industrial Property. Deposit: 08/21/2014; Concession: 08/21/2014.
1. MORTARI, M.R.; ANJOS, L.C. Peptide modified from the venom of the social wasp and its use as antiepileptic and neuroprotector. 2014, Brazil. Patent: Privilege of Innovation. Registration number: BR1020140047280, Registration institution: INPI - National Institute of the Industrial Property. Deposit: 02/27/2014; Deposit PCT: 02/27/2014; Concession: 02/27/2014.
Premiações
8. GOMES, F.M.M.; MORTARI, M.R. Second best photography at the Photography Competition (Technical Category) of the VII Animal Biology Symposium from UnB - From Basics To Translational. Title: "Astrocytes from the hippocampal formation CA3 layer immunestained by anti-GFAP, in red, and cell nucleus stained by DAPI in blue". 2016, Brasília.
7. MORTARI, M.R. Semifinalist at Santander Universities award - Science and innovation. Title: "Novel neuroprotectors peptides for the Parkinson's Disease and Epilepsy isolated from social wasp venom". 2015, Brazil.
6. MORTARI, M.R. Semifinalist at Santander Universities award - Science and innovation. Title: "Novel neuroprotectors drugs for the Parkinson's Disease: peptides isolated from social wasp venom". 2014, Brazil.
5. GOMES, F.M.M.; PANIAGO, C.K.; FREIRE, D.O.; MORTARI, M.R. Honorable Mention at 19º Scientific Initiation Congress of DF and 10º Scientific Initiation Congress of UnB. Title: "Fractionation of anticonvulsants peptides from the social wasp Synoeca sp by high performance liquid chromatography". 2013, Brasília.
4. GOMES, F.M.M.; GONÇALVES, J.C.; ARAÚJO, B.R.; COUTO, L.L.; DOS ANJOS, L.C.; SILVA, J.C.; MORTARI, M.R. MALCHER-LOPES, R. Best poster presented at IV Animal Biology Symposium from UnB. Title: "Fasting effects on the controlling of induced seizures". 2012, Brasília.
3. MOURÃO, C.A.; DOS ANJOS, L.C.; COUTO, L.L.; GONÇALVES, J.C.; MORTARI, M.R. Best work for session at Life Sciences area at the 8º Scientific Initiation Congress of DF and XVII Scientific Initiation Congress of UnB. Title: "Chemical characterization and neuropharmacological analysis of an anxiolytic compound isolated from the venom of the social wasp Polybia paulista". 2011, Brasília.
2. GOMES, F.M.M.; MORTARI, M.R.; MALCHER-LOPES R. Honorable Mention for the second best scientific initiation project at Life Sciences area at the 8º Scientific Initiation Congress of DF and XVII Scientific Initiation Congress of UnB. Title: "Influence of endogenous cannabinoids produced during fasting on seizures genesis". 2011, Brasília.
1. SILVA, J.C.; COUTO, L.L.; MOURÃO, C.A.; FERREIRA, L.B.; MORTARI, M.R. Best work for session at Life Sciences area at the 7º Scientific Initiation Congress of DF and XVI Scientific Initiation Congress of UnB. Title: "Separation by high performance liquid chromatography of neuractive peptides from the venom of the social wasp Polybia paulista". 2010, Brasília.
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